Description

2-Propanone, 1,1-Difluoro-3-Phenyl- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a phenyl ring and a difluoromethyl ketone moiety, makes it a valuable precursor for introducing fluorinated motifs into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine atoms can improve activity and environmental profile.
• Material Science Research: Serves as a monomer or precursor for synthesizing fluorinated polymers with specialized properties like chemical resistance or low surface energy.
• Organic Synthesis Building Block: Employed in various name reactions (e.g., Grignard, nucleophilic addition) to construct complex, fluorinated organic molecules for research purposes.
• Ligand and Catalyst Development: Useful for creating novel fluorinated ligands in coordination chemistry and catalysis research.

Basic Information

Product Name	2-Propanone, 1,1-Difluoro-3-Phenyl-
CAS No.	61153-49-9
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1,1-Difluoro-3-phenylacetone; 3-Phenyl-1,1-difluoroacetone; 1,1-Difluoro-3-phenylpropan-2-one; 3-Phenyl-1,1-difluoropropan-2-one; α,α-Difluoro-β-phenylacetone; (3-Phenyl-1,1-difluoropropan-2-one); Phenyl difluoromethyl ketone (related); DFPA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1,1-Difluoro-3-Phenyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.