Description

2-[(2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl)Thio]Acetonitrile is a high-purity, protected thioglycoside building block essential for advanced organic synthesis. This compound matters as a critical intermediate for the precise construction of complex carbohydrate mimetics and glycoconjugates, enabling research and development in targeted therapeutics. It is primarily needed by pharmaceutical R&D teams, process chemists, and academic researchers working on glycosidase inhibitors, antiviral agents, and novel carbohydrate-based probes. Its well-defined structure provides a reliable starting point for sophisticated medicinal chemistry programs.

Application

• Glycosidase Inhibitor Synthesis: A key precursor in the development of potent and selective glycosidase inhibitors for therapeutic applications.
• Antiviral Drug Research: Serves as a crucial building block for synthesizing nucleoside analogs and other carbohydrate-derived antiviral candidates.
• Glycoconjugate Preparation: Used in the chemical synthesis of neoglycoconjugates for vaccine development and targeted drug delivery systems.
• Chemical Biology Probes: Enables the creation of activity-based probes and labeled carbohydrates for studying glycosylation processes and enzyme mechanisms.
• Process Chemistry Intermediate: Provides a protected, reactive handle for scalable synthesis of complex oligosaccharides and glycopeptides.
• Academic & Institutional Research: Supports fundamental studies in carbohydrate chemistry and the exploration of new synthetic methodologies.

Basic Information

Product Name	2-[(2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl)Thio]Acetonitrile
CAS No.	61145-39-9
Molecular Formula	C₁₆H₂₁NO₉S
Molecular Weight	403.40 g/mol
Synonyms	2-[(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)thio]acetonitrile; 1-Thio-α-D-mannopyranoside, 2,3,4,6-tetraacetate, 2-cyanoethyl; Acetonitrile, [(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)thio]-; Tetra-O-acetyl-α-D-mannopyranosyl thiocyanatomethane; α-D-Mannopyranosyl thioacetonitrile tetraacetate; Protected Mannosyl Thioacetonitrile; 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl thiocyanate analog
EINECS	Contact for details

Quality Control

Our 2-[(2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl)Thio]Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.