Description

Cyano Methyl-2-3-4-6-Tetra-o-Acetyl-1-Th Io-B-D- is a key thioglycoside intermediate, specifically a protected derivative of a 1-thio sugar. This compound is of significant value in synthetic organic chemistry, particularly in the stereoselective construction of complex carbohydrate mimetics and nucleoside analogs. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents, antiviral drugs, and glycomimetics.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Glycomimetic Synthesis: Used in the preparation of thioglycosides, which serve as stable mimics or probes for studying carbohydrate-protein interactions.
• Oligosaccharide Assembly: Acts as a glycosyl donor in chemical glycosylation reactions for constructing complex oligosaccharide chains.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new drug candidates targeting various diseases.
• Bioconjugation Chemistry: The thio functionality can be utilized for linking carbohydrate motifs to other molecules, such as proteins or solid supports.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.

Basic Information

Item	Details
Product Name	Cyano Methyl-2-3-4-6-Tetra-o-Acetyl-1-Th Io-B-D-
CAS No.	61145-35-5
Molecular Formula	C15H19NO9S
Molecular Weight	389.38 g/mol
Synonyms	1-Thio-β-D-glucopyranose tetraacetate, cyanomethyl derivative; 2,3,4,6-Tetra-O-acetyl-1-S-cyanomethyl-1-thio-β-D-glucopyranose; Cyanomethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside; 1-S-Cyanomethyl-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranose; Thioglycoside donor intermediate; Protected 1-thio-glucose derivative
EINECS	Contact for details

Quality Control

Every batch of Cyano Methyl-2-3-4-6-Tetra-o-Acetyl-1-Th Io-B-D- is subjected to rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant spectroscopic methods. Our quality management system is designed to meet the stringent requirements of research and development and pre-clinical manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and purity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.