Description

Z-β-Ala-Val-Oh CAS NO 61058-48-8 is a protected dipeptide building block, specifically the Z-protected derivative of β-alanine and valine. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering controlled reactivity for selective amide bond formation. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of peptide chains on resin.
• Solution-Phase Peptide Synthesis: Used in the synthesis of peptide fragments and small peptides in solution.
• Medicinal Chemistry Research: Serves as a building block for creating novel peptide-based drug candidates and libraries for screening.
• Process Development & Scale-Up: Employed in the optimization and manufacturing of peptide APIs under GMP conditions.
• Bioconjugation: Can be used to introduce specific amino acid sequences into larger biomolecules or linkers.
• Biochemical Research: Utilized in the study of enzyme substrates, inhibitors, and protein-protein interactions.

Basic Information

Product Name	Z-β-Ala-Val-Oh
CAS No.	61058-48-8
Molecular Formula	C₁₈H₂₆N₂O₅
Molecular Weight	350.41 g/mol
Synonyms	N-Carbobenzoxy-β-alanyl-L-valine; Z-β-Ala-L-Val-OH; Benzyloxycarbonyl-β-alanyl-L-valine; (S)-2-((3-((((Benzyloxy)carbonyl)amino)propanoyl)amino)-3-methylbutanoic acid; CBZ-β-Ala-Val-OH; Z-β-Ala-Val; Nα-Z-β-alanyl-L-valine; N-Cbz-β-alanyl-L-valine
EINECS	Contact for details

Quality Control

Our Z-β-Ala-Val-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and MS. Our quality commitment supports applications from research to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.