Description

Carbobenzyloxy-β-Alanyl-L-Valine Benzyl Ester is a protected dipeptide building block of significant importance in synthetic organic and medicinal chemistry. This compound is a crucial intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in both Fmoc and Boc solid-phase peptide synthesis (SPPS) protocols to introduce the β-alanyl-L-valine sequence.
• Bioconjugation: Serves as a precursor for creating peptide tags, linkers, and carriers in antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Research: Employed in the study of enzyme substrates, inhibitors, and receptor ligands to understand biological pathways.
• Proteomics: Useful in the design and synthesis of standardized peptides for mass spectrometry calibration and protein analysis.
• Material Science: Potential monomer for creating novel bio-inspired polymers and hydrogels with specific functional properties.

Basic Information

Product Name	Carbobenzyloxy-β-Alanyl-L-Valine Benzyl Ester
CAS No.	61058-46-6
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Z-β-Ala-Val-OBzl; Cbz-β-Ala-L-Val-OBzl; N-Carbobenzyloxy-β-alanyl-L-valine benzyl ester; Benzyl N-[(benzyloxy)carbonyl]-β-alanyl-L-valinate; Z-β-Ala-Val-OBzl; (S)-Benzyl 3-((((benzyloxy)carbonyl)amino)propanoyl)valinate; Z-β-Ala-Val-OBz; CBZ-β-Ala-Val-OBzl
EINECS	Contact for details

Quality Control

Our Carbobenzyloxy-β-Alanyl-L-Valine Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.