Description

1-Formyl-2-Methoxypyrrolidine is a versatile heterocyclic building block and specialty reagent with significant utility in advanced organic synthesis. Its value lies in its dual functional groups, which make it a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyrrolidine scaffolds.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and protease inhibitors due to its structural similarity to proline derivatives.
• Ligand and Catalyst Synthesis: Acts as a precursor for chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Agrochemical Development: Employed in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Utilized in the synthesis of specialty polymers and functional materials requiring specific heterocyclic motifs.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Formyl-2-Methoxypyrrolidine
CAS No.	61020-06-2
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	2-Methoxy-1-pyrrolidinecarboxaldehyde; N-Formyl-2-methoxypyrrolidine; 1-Pyrrolidinecarboxaldehyde, 2-methoxy-; 2-Methoxy-N-formylpyrrolidine; 2-Methoxypyrrolidine-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Formyl-2-Methoxypyrrolidine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided with every shipment and are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.