Description

Aquomethemoglobin is a stable, oxidized form of hemoglobin where the heme iron is in the ferric (Fe³⁺) state, complexed with a water molecule. This compound is a critical biochemical standard and research reagent, essential for studying hemoglobinopathies, oxidative stress, and the development of diagnostic assays. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in hematology, clinical chemistry, and life science research.

Application

• Biochemical Research Standard: Used as a reference material for calibrating spectrophotometers and validating analytical methods in hemoglobin studies.
• Clinical Diagnostics Development: Serves as a key component in the research and quality control of diagnostic kits for detecting methemoglobinemia and other blood disorders.
• Oxidative Stress Studies: Employed as a model compound to investigate free radical biology, antioxidant mechanisms, and protein oxidation in biological systems.
• Pharmaceutical Research: Used in preclinical studies to evaluate drug interactions with hemoglobin and assess potential toxicological effects.
• Educational & Teaching Tool: Provides a stable sample for university and college laboratory courses in biochemistry, physiology, and medical technology.
• Spectrophotometric Calibration: Acts as a known absorbance standard at specific wavelengths due to its distinct and stable spectral properties.

Basic Information

Product Name	Aquomethemoglobin
CAS No.	61008-19-3
Molecular Formula	C2952H4664N812O832S8Fe4 (for human hemoglobin α2β2 tetramer)
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Methemoglobin (Aquo Complex); Hemiglobin; Ferrihemoglobin; Oxidized Hemoglobin; Hi; Hemoglobin (Ferric); MetHb; Hematin Globulin
EINECS	Contact for details

Quality Control

Our Aquomethemoglobin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques including UV-Vis spectrophotometry and electrophoresis to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, spectral characteristics, and physical form is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Avoid repeated freeze-thaw cycles. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Brown to dark red lyophilized powder or solution
Identification (UV-Vis)	Characteristic spectrum with maxima at ~405 nm and ~630 nm
Purity (Electrophoresis)	≥ 90% (as methemoglobin)
Protein Content (Biuret)	Contact for details
Solubility	Soluble in water or buffer
pH (in solution)	6.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.