Description

1,2-Diamino-5-Trifluoromethylbenzimidazole is a high-value, multi-functional heterocyclic building block characterized by its unique benzimidazole core and trifluoromethyl substituent. This compound is essential for advanced organic synthesis, offering a versatile scaffold for creating complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the benzimidazole moiety.
• Ligand Synthesis: Serves as a versatile ligand or chelating agent in coordination chemistry and catalysis.
• Material Science: Employed in the research of advanced polymers, dyes, and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	1,2-Diamino-5-Trifluoromethylbenzimidazole
CAS No.	60882-70-4
Molecular Formula	C8H7F3N4
Molecular Weight	216.17 g/mol
Synonyms	5-(Trifluoromethyl)-1H-benzimidazole-1,2-diamine; 5-(Trifluoromethyl)-2-benzimidazolediamine; 1,2-Diamino-5-(trifluoromethyl)benzimidazole; 2-Amino-5-(trifluoromethyl)-1H-benzimidazol-1-amine; 5-Trifluoromethylbenzimidazole-1,2-diamine; 1H-Benzimidazole-1,2-diamine, 5-(trifluoromethyl)-; 60882-70-4
EINECS	Contact for details

Quality Control

Our 1,2-Diamino-5-Trifluoromethylbenzimidazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.