Description

Lithium Prop-1-Ynyllithium 3-Oxide is a highly reactive organolithium compound, a key reagent in advanced synthetic organic chemistry. Its unique structure, featuring a lithium acetylide moiety, makes it an essential building block for the formation of complex carbon-carbon bonds. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for the introduction of acetylene units and the construction of complex heterocyclic scaffolds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators requiring specific alkyne functionalities.
• Advanced Material Precursor: Serves as a key monomer or initiator in the development of specialty polymers, conductive materials, and liquid crystals.
• Fine Chemical Manufacturing: Employed in the production of high-value specialty chemicals, flavors, and fragrances where precise carbon chain elongation is required.
• Academic & Industrial R&D: A fundamental tool in methodological organic chemistry research for developing new catalytic cycles and reaction methodologies.
• Lithium Chemistry Studies: Used as a model compound for investigating the reactivity and structural properties of organolithium reagents.

Basic Information

Product Name	Lithium Prop-1-Ynyllithium 3-Oxide
CAS No.	60851-89-0
Molecular Formula	C3H3Li2O
Molecular Weight	71.94 g/mol
Synonyms	Lithium(1+) 3-oxidoprop-1-yn-1-ide; Dilithium propynolate; Propynoic acid, dilithium salt; Lithium acetylide, lithium oxide adduct; 3-Oxoprop-1-yn-1-ide lithium; Lithium propiolate, dilithium salt; Propiolic acid dilithium salt
EINECS	Contact for details

Quality Control

Our Lithium Prop-1-Ynyllithium 3-Oxide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and suitability for sensitive organometallic reactions. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and moisture content is provided with every shipment. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area. Due to its pyrophoric nature and sensitivity to moisture and oxygen, this material must be handled exclusively under an inert atmosphere using appropriate Schlenk line or glovebox techniques. Recommended storage temperature: 2°C to 8°C. Keep away from heat, sparks, open flames, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Active Lithium Content	Contact for details
Moisture (KF)	≤ 0.5%
Solubility	Soluble in THF, ethers; reacts with protic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.