Description

1-(3-Methylbutanoyl)Proline is a specialized proline derivative, a key building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral and structural motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of protease inhibitors and other bioactive molecules.
• Peptidomimetics Research: Used in the design and development of peptide analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides and fungicides with specific stereochemical requirements.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and catalysts.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1-(3-Methylbutanoyl)Proline
CAS No.	60804-39-9
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	L-Proline, 1-(3-methyl-1-oxobutyl)-; 1-Isovalerylproline; (S)-1-(3-Methylbutanoyl)pyrrolidine-2-carboxylic acid; 1-(3-Methylbutyryl)proline; N-Isovaleryl-L-proline; N-(3-Methylbutanoyl)-L-proline; 2-Pyrrolidinecarboxylic acid, 1-(3-methyl-1-oxobutyl)-, (S)-
EINECS	Contact for details

Quality Control

Our 1-(3-Methylbutanoyl)Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.