Description

Cathepsin H is a lysosomal cysteine protease belonging to the papain superfamily, playing a crucial role in intracellular protein turnover and antigen presentation. This enzyme is essential for research in proteolytic pathways, cellular metabolism, and disease mechanisms. It is a vital reagent for pharmaceutical R&D, diagnostic assay development, and biochemical studies in academic and industrial laboratories globally.

Application

• Biomedical Research: Used as a key enzyme in studying lysosomal function, protein degradation, and apoptosis pathways.
• Drug Discovery & Development: Serves as a target or tool compound for screening and developing inhibitors for conditions like cancer, osteoporosis, and inflammatory diseases.
• Diagnostic Reagent Manufacturing: Employed in the production of enzymatic assay kits for clinical and research use.
• Proteomics & Biochemistry: Utilized for peptide mapping, protein sequencing, and the study of enzyme kinetics and specificity.
• Cell Biology Studies: Applied in research focused on autophagy, antigen processing, and other cellular processes involving cysteine proteases.

Basic Information

Product Name	Cathepsin H
CAS No.	60748-73-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cathepsin H (Human Liver); Cathepsin H (Bovine Spleen); Lysosomal Cysteine Protease H; Aminopeptidase B; EC 3.4.22.16; CTSH; Cathepsin H1
EINECS	Contact for details

Quality Control

Our Cathepsin H is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, specific activity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (by SDS-PAGE/HPLC), specific activity, and absence of contaminating proteases is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot reconstituted material to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Activity)	Conforms
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ 10 units/mg protein
Protein Content (Biuret)	Contact for details
pH (in solution)	3.5 - 4.5
Endotoxin	< 1.0 EU/μg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.