Description

Gastrin 17 is a specific peptide hormone fragment, also known as Gastrin I, with the CAS registry number 60748-06-3. This compound is of significant value in biochemical research and diagnostic development due to its role in stimulating gastric acid secretion. It is primarily needed by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on gastroenterology and endocrinology.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of gastrointestinal physiology, hormone-receptor interactions, and digestive processes.
• Diagnostic Development: Serves as a critical antigen and calibrator in the development and validation of immunoassays (ELISA, RIA) for measuring gastrin levels in clinical samples.
• Pharmaceutical R&D: Employed in drug discovery programs targeting gastrin receptors (CCK2R) for potential therapies related to acid-related disorders and certain cancers.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of gastrin on cell proliferation, differentiation, and signaling pathways.
• Antibody Production: Utilized as an immunogen to generate specific polyclonal or monoclonal antibodies for research and diagnostic tools.
• Quality Control: Acts as a system suitability standard in the quality control of related pharmaceutical peptides and diagnostic reagents.

Basic Information

Product Name	Gastrin 17
CAS No.	60748-06-3
Molecular Formula	C97H124N20O31S
Molecular Weight	2097.2 g/mol
Synonyms	Gastrin I; Human Gastrin I; G-17; Little Gastrin; Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2; Pyr-GPWLEEEEEAYGWMDF-NH2; H-Gly-Pro-Trp-Leu-(Glu)5-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
EINECS	Contact for details

Quality Control

Our Gastrin 17 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to cGMP guidelines for the manufacture of peptide APIs for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.