Description

Cathepsin L is a lysosomal cysteine protease enzyme that plays a critical role in intracellular protein degradation and turnover. Its precise activity is essential for research in cellular processes, including apoptosis, antigen presentation, and extracellular matrix remodeling. This high-purity enzyme is vital for pharmaceutical R&D, biochemical studies, and diagnostic kit development, serving biotechnology companies, academic research institutions, and diagnostic manufacturers globally. Cathepsin L CAS NO 60616-82-2 is supplied with guaranteed activity and stability for reproducible experimental results.

Application

• Biomedical Research: Used as a key reagent in studies of proteolytic pathways, cancer metastasis, and neurodegenerative diseases.
• Drug Discovery & Development: Employed in high-throughput screening assays to identify and characterize novel protease inhibitors as therapeutic candidates.
• Diagnostic Manufacturing: Integrated as a critical component in enzymatic assay kits for clinical diagnostics and research use.
• Cell Biology Studies: Applied to investigate mechanisms of autophagy, lysosomal function, and programmed cell death.
• Protein Biochemistry: Utilized for controlled protein digestion and peptide mapping in structural and functional proteomics.
• Viral Entry Research: Studied for its role in processing viral envelope proteins, relevant to virology and vaccine development.

Basic Information

Product Name	Cathepsin L
CAS No.	60616-82-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cathepsin L1; CTSL; Cathepsin L1 precursor; Major excreted protein (MEP); Cathepsin L (human liver); EC 3.4.22.15
EINECS	Contact for details

Quality Control

Our Cathepsin L is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for specific activity, purity, and stability, with testing aligned with relevant biochemical and research-grade standards. A comprehensive Certificate of Analysis (COA), detailing assay results, purity profile, and storage stability data, is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For extended stability, aliquot the contents upon receipt to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Activity)	Conforms
Specific Activity	≥ 40 units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported per COA
Solubility	Fully soluble in appropriate assay buffer
Endotoxin Level	< 1.0 EU/μg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.