Description

Hemoglobin J Jackson is a specific variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This product is essential for biochemical research, diagnostic development, and the study of hemoglobinopathies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and clinical diagnostics sectors for applications requiring a well-characterized hemoglobin standard.

Application

• Biochemical Research: Used as a reference standard in studies of protein structure, function, and oxygen-binding kinetics.
• Diagnostic Development: Serves as a critical component in the calibration and validation of clinical analyzers and point-of-care testing devices for hemoglobin analysis.
• Hematology Studies: Employed in research focused on hemoglobin disorders (hemoglobinopathies) and comparative studies of hemoglobin variants.
• Pharmaceutical R&D: Acts as a model protein in drug discovery programs targeting blood-related conditions and in the development of blood substitutes.
• Quality Control: Functions as a control material in laboratory settings to ensure the accuracy and precision of hemoglobin quantification methods.
• Educational Purposes: Used in academic and training laboratories for teaching advanced concepts in biochemistry and molecular biology.

Basic Information

Product Name	Hemoglobin J Jackson
CAS No.	60605-02-9
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb J Jackson; Hemoglobin variant J Jackson; α-2 globin chain variant; Unstable hemoglobin J Jackson; Hemoglobin alpha 2 6(A4) Asp->Asn (AAG->AAC); HBA2 c.19G>A; Hemoglobin J alpha; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Hemoglobin J Jackson is produced and handled under stringent quality protocols. Each batch is characterized to ensure identity, purity, and functional integrity, making it suitable for research and diagnostic applications. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), spectral properties, and functional assays are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For extended storage, consider aliquoting and freezing at -20°C or below under inert conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / HPLC)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	< 5%
Oxygen Binding Capacity	Assessed per batch
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.