Description

L-Phenylalanine, 4-Chloro-, Methyl Ester, Hydrochloride is a high-purity, chiral amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified phenylalanine residues, altering peptide stability and bioactivity.
• Medicinal Chemistry Research: Serves as a precursor for creating compound libraries to screen for biological activity against various disease targets.
• Biochemical Tool Development: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and fluorescent probes for biochemical assays.
• Agrochemical Research: Potential intermediate in the development of novel, chiral agrochemicals with specific modes of action.

Basic Information

Product Name	L-Phenylalanine, 4-Chloro-, Methyl Ester, Hydrochloride
CAS No.	60594-65-2
Molecular Formula	C10H13ClNO2 • HCl
Molecular Weight	264.58 g/mol (Free base: 227.67 g/mol)
Synonyms	(2S)-2-Amino-3-(4-chlorophenyl)propanoic acid methyl ester hydrochloride; Methyl L-4-chlorophenylalaninate hydrochloride; L-4-Chlorophenylalanine methyl ester hydrochloride; 4-Chloro-L-phenylalanine methyl ester HCl; (S)-Methyl 2-amino-3-(4-chlorophenyl)propanoate hydrochloride; Phenylalanine, 4-chloro-, methyl ester, hydrochloride, L-; Methyl (S)-2-amino-3-(4-chlorophenyl)propionate hydrochloride
EINECS	Contact for details

Quality Control

Our L-Phenylalanine, 4-Chloro-, Methyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.