Description

2-Amino-3-Methylbutanenitrile Hydrochloride is a versatile chiral building block and intermediate in organic synthesis. Its value lies in its protected amino and nitrile functionalities, which are crucial for constructing complex molecules in a controlled manner. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in the development of amino acid analogs and peptidomimetics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereochemistry for efficacy.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances where structural precision is paramount.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition and metabolic pathways.
• Peptide Chemistry: Useful in the preparation of non-natural amino acid derivatives for peptide modification and engineering.

Basic Information

Product Name	2-Amino-3-Methylbutanenitrile Hydrochloride
CAS No.	60586-49-4
Molecular Formula	C6H11N2Cl
Molecular Weight	146.62 g/mol
Synonyms	L-Valine Nitrile Hydrochloride; (S)-2-Amino-3-methylbutyronitrile Hydrochloride; 2-Amino-3-methylbutyronitrile Hydrochloride; Valinenitrile Hydrochloride; 3-Methyl-2-aminobutanenitrile Hydrochloride; (2S)-2-Amino-3-methylbutanenitrile hydrochloride; 60586-49-4
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methylbutanenitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.