Description

7-o-Demethyl Prazosin is a key pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is primarily utilized in the synthesis and analytical characterization of related active pharmaceutical ingredients (APIs). It is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on cardiovascular and urological drug development, where precise chemical standards are required for quality control and regulatory submissions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Prazosin and its structural analogs.
• Analytical Reference Standard: Used for method development, validation, and quality control (QC/QA) testing in pharmaceutical analysis.
• Metabolite Studies: Employed in pharmacokinetic and drug metabolism research to identify and quantify metabolic pathways.
• Impurity Profiling: Serves as a certified impurity standard to monitor and control the purity of bulk drug substances.
• Research & Development: A vital tool in medicinal chemistry for structure-activity relationship (SAR) studies and new drug discovery.
• Regulatory Compliance: Supports regulatory filings (e.g., with FDA, EMA) by providing a characterized standard for identity and purity tests.

Basic Information

Product Name	7-o-Demethyl Prazosin
CAS No.	60548-06-3
Molecular Formula	C₁₉H₂₁N₅O₄
Molecular Weight	383.40 g/mol
Synonyms	7-Desmethyl Prazosin; 7-Hydroxy Prazosin; Prazosin Impurity C; 2-[4-(2-Furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine; 4-Amino-6,7-dimethoxy-2-[4-(2-furoyl)-1-piperazinyl]quinazoline; 7-O-Desmethylprazosin; FR-7; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-o-Demethyl Prazosin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets high-grade standards suitable for pharmaceutical R&D and reference standard applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.