Description

H-D-Thr-Ome Hcl CAS NO 60538-15-0 is a high-purity, protected amino acid derivative, specifically the hydrochloride salt of H-D-Threonine methyl ester. This compound is a critical chiral building block in the synthesis of complex peptides and pharmaceutical intermediates, offering precise stereochemical control. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where high-quality, reliable starting materials are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected threonine derivative to prevent side reactions.
• Biochemical Research: Employed in proteomics research, enzyme substrate studies, and the development of diagnostic reagents.
• Fine Chemical Production: Serves as a building block for creating specialized catalysts, ligands, and complex organic molecules.
• Academic & R&D Laboratories: Utilized in university and corporate research for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	H-D-Thr-Ome Hcl
CAS No.	60538-15-0
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	H-D-Threonine methyl ester hydrochloride; (2R,3S)-2-Amino-3-hydroxybutyric acid methyl ester hydrochloride; Methyl (2R,3S)-2-amino-3-hydroxybutanoate hydrochloride; D-Threonine methyl ester HCl; D-Thr-OMe·HCl; Methyl D-threoninate hydrochloride; (2R,3S)-Methyl 2-amino-3-hydroxybutanoate hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Thr-Ome Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical development and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.