Description

Cephapirin Lactone is a key intermediate in the synthesis of the first-generation cephalosporin antibiotic, Cephapirin. This high-purity compound is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily utilized by pharmaceutical manufacturers and research institutions involved in antibiotic development and production.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of Cephapirin Sodium, an injectable antibiotic.
• Antibiotic Research & Development: Serves as a reference standard and starting material for developing new cephalosporin derivatives and studying structure-activity relationships.
• Veterinary Medicine Production: Used in the manufacture of intramammary infusions for the treatment of bovine mastitis.
• Quality Control & Analytical Standards: Employed as a certified reference material (CRM) in HPLC and other analytical methods for impurity profiling and assay validation.
• Process Chemistry: Integral to scale-up and optimization of fermentation and semi-synthetic processes for β-lactam antibiotics.

Basic Information

Product Name	Cephapirin Lactone
CAS No.	60517-75-1
Molecular Formula	C17H17N3O6S2
Molecular Weight	423.46 g/mol
Synonyms	(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(4-pyridinylthio)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, δ-Lactone; Cephapirin δ-Lactone; BL-P 1322 Lactone; 7-(Pyrid-4-yl-thioacetamido)cephalosporanic Acid Lactone; Cephapirin Lactone Form
EINECS	Contact for details

Quality Control

Our Cephapirin Lactone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.