Description

Neurotensin (9-13) is a bioactive pentapeptide fragment derived from the full neurotensin hormone. This specific sequence is crucial for research into the neurotensin receptor system and its associated signaling pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, oncology, and metabolic disorder studies. The compound offers a valuable tool for investigating receptor-ligand interactions and developing novel therapeutic agents.

Application

• Neuroscience Research: Used as a selective ligand to study the role of neurotensin receptors (NTS1 and NTS2) in the central nervous system, including their effects on dopamine modulation, pain perception, and thermoregulation.
• Pharmacological Studies: Serves as a reference standard and active agent in assays to screen for neurotensin receptor agonists, antagonists, and allosteric modulators for drug discovery programs.
• Cancer Research: Investigated for its effects on cancer cell proliferation and migration, as neurotensin receptors are overexpressed in various cancers, including pancreatic, prostate, and colon cancers.
• Biochemical Assay Development: Employed in the development and validation of receptor binding assays, ELISA kits, and other diagnostic tools targeting the neurotensin pathway.
• Academic & Institutional Research: A key reagent for fundamental studies in cell signaling, peptide biochemistry, and neuroendocrinology within university and government research laboratories.

Basic Information

Product Name	Neurotensin (9-13)
CAS No.	60482-96-4
Molecular Formula	C33H49N9O8
Molecular Weight	699.81 g/mol
Synonyms	Arg-Arg-Pro-Tyr-Ile; Arg-Arg-Pro-Tyr-Ile-OH; Neurotensin Fragment 9-13; NT (9-13); H-Arg-Arg-Pro-Tyr-Ile-OH; Pentapeptide Neurotensin (9-13); Neurotensin Pentapeptide; RRPYI; pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile (9-13 fragment)
EINECS	Contact for details

Quality Control

Our Neurotensin (9-13) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPIC)	≤ 15.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.