Description

4-Acetamidobenzoylglutamate is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel therapeutic agents and biochemical probes. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery, particularly in the areas of targeted cancer therapies and enzyme inhibitor design.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly folate analogs and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and enzyme function.
• Anticancer Agent Development: Serves as a precursor in the research and development of targeted chemotherapeutic compounds.
• Peptidomimetic Synthesis: Incorporated into peptide-like structures to enhance stability, bioavailability, and biological activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Prodrug Design: Utilized in the development of prodrugs to improve the delivery and efficacy of active pharmaceutical ingredients.

Basic Information

Product Name	4-Acetamidobenzoylglutamate
CAS No.	60474-41-1
Molecular Formula	C14H16N2O6
Molecular Weight	308.29 g/mol
Synonyms	N4-Acetyl-p-aminobenzoyl-L-glutamic Acid; N-Acetyl-PABA-Glutamate; L-Glutamic acid, N-[4-(acetylamino)benzoyl]-; 4-Acetamidobenzoic acid glutamate; PGA-amide derivative; Ac-PABA-Glu; Folate analog intermediate; 4-Acetamidobenzoyl-L-glutamic acid
EINECS	Contact for details

Quality Control

Our 4-Acetamidobenzoylglutamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.