Description

2-Cyclobuten-1-One, 2,4,4-Trifluoro-3-Methoxy- is a highly functionalized, fluorinated cyclobutenone derivative that serves as a versatile and valuable synthetic intermediate. Its unique structure, featuring a reactive ketone within a strained four-membered ring and electron-withdrawing fluorine substituents, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or strained ring systems for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorinated cyclobutenone core imparts unique biological activity.
• Advanced Material Synthesis: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials with tailored properties.
• Organic Synthesis Building Block: Employed in [4+2] cycloaddition reactions and ring-opening transformations to access complex, polyfunctionalized organic frameworks not easily obtained by other routes.
• Fluorine Chemistry Research: A valuable substrate for studying the reactivity and effects of fluorine atoms in strained, unsaturated systems.

Basic Information

Product Name	2-Cyclobuten-1-One, 2,4,4-Trifluoro-3-Methoxy-
CAS No.	60407-10-5
Molecular Formula	C5H3F3O2
Molecular Weight	152.07 g/mol
Synonyms	2,4,4-Trifluoro-3-methoxy-2-cyclobuten-1-one; 3-Methoxy-2,4,4-trifluorocyclobut-2-en-1-one; 2-Cyclobuten-1-one, 2,4,4-trifluoro-3-methoxy-; Trifluoromethoxycyclobutenone; 2,4,4-Trifluoro-3-methoxycyclobut-2-enone
EINECS	Contact for details

Quality Control

Our 2-Cyclobuten-1-One, 2,4,4-Trifluoro-3-Methoxy- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.