Description

(E)-2-Oxo-4-Phenylbut-3-Enenitrile is a versatile α,β-unsaturated carbonyl nitrile compound, serving as a crucial synthetic intermediate in advanced organic chemistry. Its conjugated system makes it a valuable electrophile for Michael additions and a precursor for heterocyclic synthesis, enabling the construction of complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various heterocyclic compounds, including pyridines, pyrimidines, and pyrroles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators, leveraging its reactivity to create novel bioactive molecules.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers where its phenyl and nitrile groups impart specific electronic or structural properties.
• Academic & R&D: A valuable reagent in methodological development and discovery chemistry for studying conjugate addition reactions and cyclization processes.
• Material Science: Potential monomer or cross-linking agent in the development of specialty resins and polymers with tailored thermal or optical characteristics.

Basic Information

Product Name	(E)-2-Oxo-4-Phenylbut-3-Enenitrile
CAS No.	60299-77-6
Molecular Formula	C10H7NO
Molecular Weight	157.17 g/mol
Synonyms	(E)-2-Oxo-4-phenyl-3-butenenitrile; 4-Phenyl-3-buten-2-one-1-nitrile; 2-Oxo-4-phenyl-3-butenenitrile; Benzylideneacetonitrile, 2-oxo-; (E)-4-Phenylbut-3-ene-2-onenitrile; 3-Butenenitrile, 2-oxo-4-phenyl-, (E)-; α-Benzylideneacetoacetonitrile; (E)-2-Cyano-4-phenylbut-3-en-2-one
EINECS	Contact for details

Quality Control

Our (E)-2-Oxo-4-Phenylbut-3-Enenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	85 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.