Description

4-(4-Fluoroanilino)-4-Oxobut-2-Enoic Acid is a specialized fluorinated organic intermediate featuring a reactive α,β-unsaturated carbonyl system. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aniline and maleimide motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluorophenyl group enhances biological activity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional organic materials.
• Chemical Synthesis: Acts as a Michael acceptor in organic synthesis for the construction of complex molecular architectures via conjugate addition reactions.
• Bioconjugation: Potential use in bioconjugation chemistry for labeling proteins or other biomolecules due to its reactive double bond.
• Academic & Industrial R&D: A valuable reagent for methodological studies and discovery chemistry in both academic and industrial laboratory settings.

Basic Information

Product Name	4-(4-Fluoroanilino)-4-Oxobut-2-Enoic Acid
CAS No.	60252-79-1
Molecular Formula	C10H8FNO3
Molecular Weight	209.17 g/mol
Synonyms	4-(4-Fluorophenylamino)-4-oxo-2-butenoic acid; (2E)-4-[(4-Fluorophenyl)amino]-4-oxo-2-butenoic acid; 4-Fluoroanilinomaleic acid; 2-Butenoic acid, 4-[(4-fluorophenyl)amino]-4-oxo-, (2E)-; N-(4-Fluorophenyl)maleamic acid; 4-Oxo-4-(4-fluoroanilino)but-2-enoic acid; Maleamic acid, N-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 4-(4-Fluoroanilino)-4-Oxobut-2-Enoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. We employ advanced analytical techniques, including HPLC, NMR, and MS, for comprehensive identity and purity verification. A Certificate of Analysis (COA) detailing specific lot results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.