Description

L-Valine, n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl- is a protected dipeptide building block, specifically a Boc-protected L-Alanyl-L-Valine derivative. This compound is essential for the controlled synthesis of peptides, providing a key intermediate for constructing specific amino acid sequences. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial intermediate for the sequential assembly of peptides in automated synthesizers.
• Solution-Phase Peptide Synthesis: Used in traditional coupling reactions for the production of custom peptides and peptide libraries.
• Pharmaceutical Research: Serves as a building block for the development of novel therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Can be employed in the synthesis of peptide-protein or peptide-small molecule conjugates for targeted drug delivery.
• Biochemical Research: Used in studies of protein structure, function, and protein-protein interactions.
• Production of Protected Peptide Fragments: For the convergent synthesis of larger, complex polypeptides and proteins.

Basic Information

Product Name	L-Valine, n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-
CAS No.	60209-59-8
Molecular Formula	C13H24N2O5
Molecular Weight	288.34 g/mol
Synonyms	Boc-L-Ala-L-Val-OH; Boc-Ala-Val-OH; N-(tert-Butoxycarbonyl)-L-alanyl-L-valine; (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-methylbutanoic acid; tert-Butoxycarbonyl-L-alanyl-L-valine; Boc-L-Alanyl-L-valine; N-Boc-L-alanyl-L-valine; L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-
EINECS	Contact for details

Quality Control

Our Boc-L-Ala-L-Val-OH is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.