Description

4-[2-(Bromomethyl)-1,3-Dioxolan-2-Yl]Benzonitrile is a high-value, multi-functional chemical intermediate featuring a reactive bromomethyl group and a protected carbonyl moiety. This compound is essential for synthetic chemists requiring precise molecular construction, particularly in the development of complex active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for its versatility in nucleophilic substitution and further functionalization reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those requiring the introduction of a benzonitrile or protected aldehyde functionality.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive sites allow for the creation of targeted bioactive molecules.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its aromatic and polar characteristics.
• Custom Chemical Synthesis: Provides a versatile handle for contract research organizations (CROs) and fine chemical manufacturers performing custom synthesis and scale-up services.

Basic Information

Product Name	4-[2-(Bromomethyl)-1,3-Dioxolan-2-Yl]Benzonitrile
CAS No.	60207-22-9
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	2-(4-Cyanophenyl)-2-(bromomethyl)-1,3-dioxolane; 4-(2-Bromomethyl-1,3-dioxolan-2-yl)benzonitrile; 2-(Bromomethyl)-2-(4-cyanophenyl)-1,3-dioxolane; p-Cyanophenyl bromomethyl dioxolane; α-Bromo-α-(4-cyanophenyl)-1,3-dioxolane; Bromomethyl dioxolane benzonitrile; (2-(Bromomethyl)-1,3-dioxolan-2-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[2-(Bromomethyl)-1,3-Dioxolan-2-Yl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.