Description

N,n-Bis-(1,3-Dihydroxy-2-Propyl)-5-Nitroisophthalamide is a specialized nitro-substituted isophthalamide derivative featuring two dihydroxypropyl arms. This compound matters for its unique molecular architecture, which combines a nitroaromatic core with hydrophilic, polyol-functionalized side chains, making it a valuable intermediate for advanced synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical and fine chemical industries for developing novel active ingredients, prodrugs, or functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring nitroaromatic or amide functionalities.
• Prodrug Development: The dihydroxypropyl groups make it a suitable linker for creating water-soluble prodrugs of active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Used as a monomer or cross-linking agent for synthesizing specialty polyamides or polyesters with specific light-absorbing or adhesive properties.
• Chemical Research: Acts as a model compound or reagent in organic synthesis and medicinal chemistry research projects.
• Coordination Chemistry: The amide and hydroxyl groups can act as ligands for metal complexation in catalytic or material science applications.

Basic Information

Product Name	N,n-Bis-(1,3-Dihydroxy-2-Propyl)-5-Nitroisophthalamide
CAS No.	60166-97-4
Molecular Formula	C14H19N3O8
Molecular Weight	357.32 g/mol
Synonyms	5-Nitroisophthalamic acid, N,N-bis(1,3-dihydroxy-2-propyl)amide; 1,3-Bis[(2,3-dihydroxypropyl)carbamoyl]-5-nitrobenzene; N,N-Bis(2,3-dihydroxypropyl)-5-nitroisophthalamide; 5-Nitro-N,N-bis(2,3-dihydroxypropyl)isophthalamide; Bis(2,3-dihydroxypropyl) 5-nitroisophthalamate (common name); DNIPA (abbreviation); Nitroisophthalamide diol derivative
EINECS	Contact for details

Quality Control

Our N,n-Bis-(1,3-Dihydroxy-2-Propyl)-5-Nitroisophthalamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0 %
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.