Description

Iopamidol is a non-ionic, water-soluble contrast medium widely used in diagnostic imaging. Its primary value lies in its excellent safety profile and high radiopacity, providing clear visualization of vascular structures and internal organs. This compound is essential for manufacturers of injectable pharmaceutical formulations targeting the medical diagnostics sector, particularly for X-ray, CT (Computed Tomography), and angiography procedures.

Application

Iopamidol is a key active pharmaceutical ingredient (API) in contrast media formulations for various diagnostic imaging techniques.

• X-ray and CT Scan Contrast Media: Formulated for intravenous injection to enhance visualization of blood vessels, organs, and tissues.
• Angiography and Arteriography: Used in procedures to image arteries, including coronary, cerebral, and peripheral angiography.
• Urography and Pyelography: Employed for imaging the urinary tract, including kidneys, ureters, and bladder.
• Myelography: Applied in imaging of the spinal canal and subarachnoid space.
• Arthrography: Used for imaging joint spaces.
• Hysterosalpingography: Utilized in imaging of the uterus and fallopian tubes.
• Pharmaceutical Intermediates: Serves as a critical starting material or intermediate in the synthesis of other specialized contrast agents.

Basic Information

Product Name	Iopamidol
CAS No.	60166-93-0
Molecular Formula	C17H22I3N3O8
Molecular Weight	777.09 g/mol
Synonyms	Iopamidol; N,N'-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide; SQ 13396; Iopamiro; Isovue; Solutrast; Niopam; Iopamiron; (S)-N,N'-Bis[(2S)-2,3-dihydroxypropyl]-5-[(2-hydroxypropionyl)amino]-2,4,6-triiodoisophthalamide
EINECS	262-081-3

Quality Control

Our Iopamidol is manufactured under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial requirements. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
pH (5% Solution)	6.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.