Description

tert-Butyl 3-Methoxyphenylcarbamate CAS NO 60144-52-7 is a high-purity, protected aniline derivative primarily used as a versatile synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyloxycarbonyl (Boc) protecting group, which provides excellent stability under a wide range of reaction conditions while being readily cleaved under mild acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a key building block for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those containing substituted aniline moieties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, where its protected amine functionality allows for selective derivatization.
• Organic Synthesis Reagent: Serves as a protected aniline source in peptide coupling reactions, palladium-catalyzed cross-couplings, and other complex organic transformations in R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and pigments that require the controlled introduction of a 3-methoxyaniline group.
• Academic & Industrial Research: A valuable tool for chemists in universities and corporate R&D centers exploring new synthetic methodologies and molecular architectures.

Basic Information

Product Name	tert-Butyl 3-Methoxyphenylcarbamate
CAS No.	60144-52-7
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	3-Methoxyphenylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(3-Methoxyphenyl)carbamate; BOC-3-Methoxyaniline; N-Boc-3-Methoxyaniline; N-(tert-Butoxycarbonyl)-3-methoxyaniline; Carbamic acid, N-(3-methoxyphenyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-(3-methoxyphenyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methoxyphenylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.