Description

Involucrin CAS NO 60108-77-2 is a high-purity biochemical reagent recognized for its role as a key structural protein component. This compound is essential for research and development in advanced dermatological and cosmetic science, where precise biological activity is paramount. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and high-end personal care industries seeking to innovate in skin biology and barrier function studies.

Application

• Biomedical Research: Used as a critical biomarker and substrate in studies of keratinocyte differentiation and epidermal barrier formation.
• Cosmetic Science & Dermocosmetics: Incorporated into advanced in-vitro models to evaluate the efficacy of anti-aging, moisturizing, and skin-repair formulations.
• Pharmaceutical Development: Serves as a reference standard and active ingredient research tool for topical therapies targeting skin disorders like psoriasis and eczema.
• Diagnostic Reagent Manufacturing: Employed in the production of assay kits and antibodies for detecting specific skin protein expression levels.
• Cell Culture & Tissue Engineering: Acts as a component in specialized media or scaffolds for cultivating skin-equivalent models.
• Academic Research: Fundamental tool in university and institutional labs for molecular biology and dermatology research projects.

Basic Information

Product Name	Involucrin
CAS No.	60108-77-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Involucrin Protein; Epidermal Cell Envelope Precursor Protein; Human Involucrin; Keratinocyte Envelope Precursor; Cell Envelope Protein; Cornified Envelope Precursor; CE Precursor Protein; Involucrin (Human)
EINECS	Contact for details

Quality Control

Our Involucrin is produced under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under desiccant or inert atmosphere after opening to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR/HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by ELISA or functional assay
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.