Description

n-((4-Chlorophenyl)Difluoromethyl)Cyclopropanamine is a specialized organofluorine compound featuring a cyclopropylamine moiety, serving as a high-value building block in advanced organic synthesis. Its unique structure, combining a halogenated aromatic ring with a difluoromethyl and a strained cyclopropane ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides, herbicides, and fungicides, where the difluoromethyl and cyclopropyl groups can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	n-((4-Chlorophenyl)Difluoromethyl)Cyclopropanamine
CAS No.	60010-38-0
Molecular Formula	C10H10ClF2N
Molecular Weight	217.64 g/mol
Synonyms	1-[(4-Chlorophenyl)(difluoro)methyl]cyclopropanamine; N-[(4-Chlorophenyl)difluoromethyl]cyclopropanamine; Cyclopropanamine, N-[(4-chlorophenyl)difluoromethyl]-; 1-((4-Chlorophenyl)difluoromethyl)cyclopropan-1-amine; 4-Chloro-α-(cyclopropylamino)-α,α-difluorotoluene; α-(Aminocyclopropyl)-4-chloro-α,α-difluorotoluene
EINECS	Contact for details

Quality Control

Our n-((4-Chlorophenyl)Difluoromethyl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.