Description

4-Nitro-1-Phenoxy-2-(Trifluoromethyl)Benzene is a specialized aromatic compound featuring nitro and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound matters as a versatile and valuable chemical intermediate for synthesizing more complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Investigated as a component in the synthesis of organic semiconductors and charge-transport materials.
• Dye and Pigment Intermediate: Utilized in the development of specialized dyes and pigments due to its nitro-aromatic structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.

Basic Information

Product Name	4-Nitro-1-Phenoxy-2-(Trifluoromethyl)Benzene
CAS No.	6969-95-5
Molecular Formula	C13H8F3NO3
Molecular Weight	283.21 g/mol
Synonyms	2-(Trifluoromethyl)-4-nitrodiphenyl ether; 1-Nitro-4-phenoxy-2-(trifluoromethyl)benzene; 4-Nitrophenyl 2-(trifluoromethyl)phenyl ether; 2-Trifluoromethyl-4-nitrodiphenyl ether; 4-Nitro-2-trifluoromethyldiphenyl ether; 1-Phenoxy-2-trifluoromethyl-4-nitrobenzene; NSC 163081
EINECS	Contact for details

Quality Control

Our 4-Nitro-1-Phenoxy-2-(Trifluoromethyl)Benzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), related substances, and physical characteristics. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.