Description

N,N'-Bis(Benzyloxycarbonyl)-L-Cystine is a protected derivative of the amino acid L-cystine, where the amine groups are shielded by benzyloxycarbonyl (Cbz or Z) protecting groups. This modification is crucial for enabling selective peptide synthesis, particularly in the pharmaceutical and biotechnology sectors where precise molecular construction is required. It serves as a key building block for researchers and manufacturers developing peptide-based drugs, diagnostic agents, and biochemical tools, ensuring the integrity of the disulfide bond during complex synthetic sequences.

Application

• Peptide Synthesis: A fundamental protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS), especially for sequences containing cystine.
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers in drug delivery system development.
• Biochemical Research: Employed in studying disulfide bond formation, protein folding, and oxidative stress pathways in academic and industrial R&D laboratories.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	N,N'-Bis(Benzyloxycarbonyl)-L-Cystine
CAS No.	6968-11-2
Molecular Formula	C22H24N2O8S2
Molecular Weight	508.56 g/mol
Synonyms	N,N'-Di-Cbz-L-cystine; (R,R)-2,2'-Disulfanediylbis(3-((benzyloxy)carbonyl)amino)propanoic acid; L-Cystine, N,N'-bis(benzyloxycarbonyl)-; Z-Cys(S-S-Cys(Z))-OH; Bis-Cbz-L-cystine; N,N'-Bis-Cbz-L-cystine; N,N'-Dicarbobenzoxy-L-cystine; N,N'-Dibenzyloxycarbonyl-L-cystine
EINECS	Contact for details

Quality Control

Our N,N'-Bis(Benzyloxycarbonyl)-L-Cystine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.