Description

5-Nitro-3-Indolylacetonitrile is a versatile and high-purity nitrile-substituted indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive nitrile and nitro functional groups, which enable the construction of complex heterocyclic scaffolds and pharmacologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Organic Synthesis: Serves as a versatile precursor for synthesizing more complex heterocycles, dyes, and functional materials via reactions at the nitrile and nitro groups.
• Biochemical Research: Employed in the study of enzyme-substrate interactions and as a scaffold for designing molecular probes and inhibitors.
• Material Science: Investigated as a monomer or additive for creating specialized polymers and advanced organic electronic materials.

Basic Information

Item	Detail
Product Name	5-Nitro-3-Indolylacetonitrile
CAS No.	6952-13-2
Molecular Formula	C10H7N3O2
Molecular Weight	201.18 g/mol
Synonyms	3-(Cyanomethyl)-5-nitro-1H-indole; 5-Nitro-1H-indole-3-acetonitrile; (5-Nitro-1H-indol-3-yl)acetonitrile; 5-Nitroindole-3-acetonitrile; 5-Nitro-3-indoleacetonitrile; 5-Nitroindol-3-ylacetonitrile; 6952-13-2; 5-Nitro-1H-indole-3-acetic acid nitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Nitro-3-Indolylacetonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are validated against in-house specifications developed for research and industrial use. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.