Description

Chloroac-Dl-Nva-Oh CAS NO 6940-47-2 is a specialized amino acid derivative, specifically a chloroacetylated norvaline, used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing specific functional groups and modifying peptide backbones, enabling the creation of novel molecular structures. It is primarily required by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, proteomics research, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediates: A key synthon in the research and development of novel peptide drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a modified amino acid residue to alter peptide properties.
• Bioconjugation: Serves as a linker or handle for attaching peptides to other molecules, surfaces, or probes in bioconjugation chemistry.
• Proteomics & Biochemical Research: Employed in the study of protein-protein interactions and enzyme mechanisms as a substrate or inhibitor analog.
• Chemical Biology Tool Development: Utilized to create chemical probes for labeling and studying biological systems.
• Material Science: Potential application in the synthesis of functionalized polymers and biomaterials.

Basic Information

Product Name	Chloroac-Dl-Nva-Oh
CAS No.	6940-47-2
Molecular Formula	C7H12ClNO3
Molecular Weight	193.63 g/mol
Synonyms	N-Chloroacetyl-DL-norvaline; 2-(Chloroacetamido)pentanoic acid; DL-2-(Chloroacetamido)valeric acid; Chloroacetyl-DL-norvaline; Norvaline, N-chloroacetyl-, DL-; (RS)-2-(2-Chloroacetamido)pentanoic acid; N-(Chloroacetyl)-DL-norvaline; DL-N-Chloroacetylnorvaline
EINECS	Contact for details

Quality Control

Our Chloroac-Dl-Nva-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.