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n-[(20S)-4β-Acetoxy-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-n-Methylbenzamide CAS NO 6879-28-3


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CAS No.:6879-28-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[(20S)-4β-Acetoxy-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-n-Methylbenzamide is a high-purity, structurally complex steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly those targeting neurological and hormonal pathways. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation steroid-based pharmaceuticals.

Application

  • Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary steroid-based active pharmaceutical ingredients (APIs).
  • Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure product identity and purity.
  • Biochemical Research: Employed in preclinical studies to investigate structure-activity relationships (SAR) and receptor binding affinities of modified steroid molecules.
  • Process Chemistry: Serves as a starting material or intermediate in process optimization and scale-up activities for new chemical entities (NCEs).
  • Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and steroid pharmacology.

Basic Information

Product Name n-[(20S)-4β-Acetoxy-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-n-Methylbenzamide
CAS No. 6879-28-3
Molecular Formula C33H48N2O3
Molecular Weight 520.75 g/mol
Synonyms 4β-Acetoxy-20-(dimethylamino)-5α-pregnan-3α-yl-N-methylbenzamide; (20S)-4β-Acetoxy-20-(dimethylamino)-5α-pregnan-3α-yl-N-methylbenzamide; 3α-(N-Methylbenzamido)-4β-acetoxy-20-(dimethylamino)-5α-pregnane; Benzamide, N-[(20S)-4β-acetoxy-20-(dimethylamino)-5α-pregnan-3α-yl]-N-methyl-; Pregnenolone acetate derivative
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Quality Control

Our n-[(20S)-4β-Acetoxy-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-n-Methylbenzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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