Description

Lithium Acetylide Ethylenediamine Complex is a highly reactive organolithium reagent used as a powerful acetylide anion source in organic synthesis. This compound matters for its ability to facilitate efficient carbon-carbon bond formation, specifically in the synthesis of terminal and internal alkynes, which are crucial building blocks in pharmaceuticals and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Alkyne Synthesis: Key reagent for the nucleophilic addition to carbonyl compounds and alkyl halides to create new carbon-carbon bonds.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates containing acetylene functionalities.
• Material Science: Building block for conjugated polymers and molecular wires in organic electronics due to its ability to introduce rigid, linear alkyne spacers.
• Agrochemicals: Employed in the production of herbicides, fungicides, and plant growth regulators that require acetylene-based structures.
• Natural Product Synthesis: Facilitates the construction of complex natural products and bioactive molecules that contain alkyne groups.
• Cross-Coupling Reactions: Serves as a precursor for Sonogashira and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	Lithium Acetylide Ethylenediamine Complex
CAS No.	6867-30-7
Molecular Formula	C4H10Li2N2
Molecular Weight	100.02 g/mol
Synonyms	Lithium Ethylenediamine Acetylide; Acetylenediylbis(lithium), compd. with 1,2-ethanediamine (1:2); 1,2- Ethanediamine, compd. with acetylenediylbis[lithium] (2:1); Lithium acetylide-ethylenediamine adduct; Lithium acetylide ethylenediamine; Lithium acetylide-EDA complex
EINECS	Contact for details

Quality Control

Our Lithium Acetylide Ethylenediamine Complex is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is tested to confirm identity, purity, and suitability for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and moisture content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be kept tightly sealed and flushed with inert gas after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Moisture (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.