Description

Dl-4-Hydroxymandelonitrile CAS NO 6851-36-1 is a versatile chiral cyanohydrin derivative, serving as a critical synthetic intermediate in fine chemical and pharmaceutical manufacturing. Its bifunctional structure, containing both hydroxyl and nitrile groups, makes it a valuable precursor for the synthesis of complex molecules, including amino acids, pharmaceuticals, and agrochemicals. This compound is essential for research and production facilities focused on asymmetric synthesis, chiral resolution, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drugs, β-blockers, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used as a precursor in the manufacture of certain herbicides and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring chiral centers.
• Research & Development: A valuable reagent in organic chemistry research for studying cyanohydrin chemistry and asymmetric catalysis.
• Amino Acid Synthesis: Serves as a starting material for the preparation of non-natural amino acids and their derivatives.

Basic Information

Product Name	Dl-4-Hydroxymandelonitrile
CAS No.	6851-36-1
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	4-Hydroxymandelonitrile; DL-4-Hydroxymandelic acid nitrile; (±)-4-Hydroxymandelonitrile; (RS)-4-Hydroxymandelonitrile; Mandelonitrile, 4-hydroxy-; p-Hydroxymandelonitrile; 2-Hydroxy-2-(4-hydroxyphenyl)acetonitrile; α-Hydroxy-4-hydroxybenzeneacetonitrile
EINECS	229-946-5

Quality Control

Our Dl-4-Hydroxymandelonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.