Description

6-Acetylcodeine is a semi-synthetic derivative of the natural alkaloid codeine, characterized by the acetylation of the phenolic hydroxyl group. This modification alters its physicochemical properties, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel analgesic compounds and the study of opioid receptor pharmacology.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of specialized opioid analgesics and antitussive agents.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control testing.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) within the opioid class of compounds.
• Controlled Substance Analog Research: Serves as a model compound in forensic and regulatory science for the development of detection methodologies.

Basic Information

Product Name	6-Acetylcodeine
CAS No.	6703-27-1
Molecular Formula	C20H23NO4
Molecular Weight	341.40 g/mol
Synonyms	6-Acetylcodeine; 3-Methoxy-6-acetoxy-17-methyl-7,8-didehydro-4,5α-epoxymorphinan; 6-O-Acetylcodeine; Codeine 6-acetate; Thebacetyline; Norcodeine 6-acetate (related); Acetylcodeine
EINECS	Contact for details

Quality Control

Our 6-Acetylcodeine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.