Description

Coenzyme A, S-(3-Hydroxy-2-Methylbutanoate) is a specialized biochemical cofactor essential for acyl group transfer reactions in metabolic pathways. This high-purity compound is critical for research and development in enzymology and metabolic studies, where precise biochemical activity is required. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of diagnostic reagents and fine biochemicals.

Application

• Biochemical Research & Enzymology: Serves as a key substrate or intermediate in the study of CoA-dependent enzymes and metabolic pathways, including fatty acid metabolism.
• Pharmaceutical Development: Used in the synthesis and research of novel drug candidates targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed as a critical component in the formulation of enzymatic assay kits for clinical and research diagnostics.
• Metabolite & Pathway Analysis: Acts as a standard or reference compound in mass spectrometry (MS) and liquid chromatography (LC-MS) for metabolomics studies.
• Fine Chemical Synthesis: Utilized as a building block or chiral auxiliary in the synthesis of complex, high-value organic molecules.

Basic Information

Product Name	Coenzyme A, S-(3-Hydroxy-2-Methylbutanoate)
CAS No.	6701-38-8
Molecular Formula	C26H42N7O17P3S
Molecular Weight	849.62 g/mol
Synonyms	3-Hydroxy-2-methylbutyryl-CoA; 3-Hydroxy-2-methylbutyryl-Coenzyme A; HMB-CoA; (3R)-3-Hydroxy-2-methylbutanoyl-CoA; S-(3-Hydroxy-2-methylbutanoyl)coenzyme A; 3-Hydroxy-2-methylbutanoate-CoA; CoA S-(3-hydroxy-2-methylbutanoate); 3-Hydroxy-2-methylbutyryl-coenzyme A
EINECS	Contact for details

Quality Control

Our Coenzyme A, S-(3-Hydroxy-2-Methylbutanoate) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.