Description

E-Chlorocapronitrile is a versatile halogenated nitrile intermediate of significant importance in advanced organic synthesis. Its primary value lies in its bifunctional reactivity, where the nitrile group and the chlorine atom serve as distinct handles for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those containing cyanoalkyl or chlorinated moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloronitrile structure is incorporated into active molecules.
• Ligand and Catalyst Development: Acts as a starting material for the preparation of specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce cyano or chloro functional groups into polymer backbones to alter material properties like solubility and thermal stability.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution reactions, cyano group transformations, and cyclization reactions to create heterocyclic compounds.

Basic Information

Product Name	E-Chlorocapronitrile
CAS No.	6628-78-0
Molecular Formula	C6H10ClN
Molecular Weight	131.60 g/mol
Synonyms	trans-2-Chlorohexenenitrile; (E)-2-Chloro-2-hexenenitrile; 2-Chlorohex-2-enenitrile; (E)-2-Chlorohex-2-enenitrile; 2-Hexenenitrile, 2-chloro-, (E)-; 2-Chloro-2-hexenenitrile (E); E-2-Chlorohex-2-enenitrile
EINECS	229-599-9

Quality Control

Our E-Chlorocapronitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Isomeric Purity (E-isomer, GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.