Description

Quinidine Sulfate Dihydrate CAS NO 6591-63-5 is a high-purity alkaloid salt widely recognized for its critical role in pharmaceutical research and manufacturing. This compound serves as a class Ia antiarrhythmic agent and a potent potassium channel blocker, making it indispensable for cardiac electrophysiology studies and drug development. It is primarily required by pharmaceutical companies, contract research organizations (CROs), and academic laboratories engaged in cardiovascular research, analytical method development, and the production of reference standards.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of antiarrhythmic medications.
• Pharmacological Research as a standard tool for studying cardiac ion channels (IKr) and arrhythmia mechanisms.
• Analytical Reference Standard for quality control (QC) and assay development in pharmaceutical laboratories.
• Biochemical Research for investigating the effects of potassium channel blockade in various cell-based assays.
• Teaching & Academic Studies in university settings for advanced pharmacology and medicinal chemistry courses.
• Preclinical Development for safety and efficacy profiling of new cardiovascular drug candidates.

Basic Information

Product Name	Quinidine Sulfate Dihydrate
CAS No.	6591-63-5
Molecular Formula	(C20H24N2O2)2·H2SO4·2H2O
Molecular Weight	782.96 g/mol
Synonyms	Quinidine Sulfate Dihydrate; Quinidine Sulphate Dihydrate; (8S,9R)-6'-Methoxycinchonan-9-ol sulfate dihydrate; Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, sulfate (2:1) (salt), dihydrate; Pitayine Sulfate Dihydrate; Conchinine Sulfate Dihydrate; β-Quinine Sulfate Dihydrate
EINECS	229-560-3

Quality Control

Our Quinidine Sulfate Dihydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	4.0% - 5.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Meets Ph. Eur. criteria for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.