Description

2-Bromo-6-Chloro-Benzonitrile CAS NO 6575-08-2 is a versatile halogenated benzonitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This high-purity compound is essential for research and development chemists and process engineers working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, leveraging its halogenated aromatic core.
• Material Science Precursor: Serves as a starting material for the synthesis of liquid crystals and organic electronic materials.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized aryl groups.
• Ligand and Catalyst Development: Useful for creating novel chelating ligands in coordination chemistry and catalysis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	2-Bromo-6-Chloro-Benzonitrile
CAS No.	6575-08-2
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	2-Bromo-6-chlorobenzonitrile; 6-Chloro-2-bromobenzonitrile; Benzonitrile, 2-bromo-6-chloro-; 2-Bromo-6-chlorobenzocarbonitrile; (2-Bromo-6-chlorophenyl)carbonitrile; NSC 403119; 6575-08-2; 2-Br-6-Cl-Bn
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and GC/MS for identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.