Description

Cyclononyne is a strained cyclic alkyne of significant interest in advanced organic synthesis and materials science. Its unique structure, featuring a nine-membered ring with a triple bond, makes it a valuable building block for click chemistry and the construction of complex molecular architectures. This compound is particularly sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel bioactive compounds and functional materials. CAS NO 6573-52-0.

Application

• Click Chemistry Reagent: A key substrate for strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, enabling bioconjugation and labeling of biomolecules without cytotoxic catalysts.
• Pharmaceutical Intermediate: Used in the synthesis of complex, strained-ring systems for potential drug candidates and molecular probes.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating novel polymers with tailored thermal and mechanical properties.
• Agrochemical Research: Employed in the development of new active ingredients with unique modes of action.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Academic & R&D: A fundamental tool for studying reaction mechanisms, ring strain, and the properties of medium-sized cycloalkynes.

Basic Information

Product Name	Cyclononyne
CAS No.	6573-52-0
Molecular Formula	C9H14
Molecular Weight	122.21 g/mol
Synonyms	Cyclonon-1-yne; 1-Cyclononyne; Cyclononyne; 9-Membered cyclic alkyne; C9-Alkyne; Medium-ring cycloalkyne; SPAAC reagent
EINECS	Contact for details

Quality Control

Every batch of Cyclononyne is produced and analyzed under strict quality protocols to ensure high purity and consistency for research and development applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and reliability, making it suitable for critical pharmaceutical and material science projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. Due to its sensitivity to oxidation, the container should only be opened in a controlled, oxygen-free environment. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95%
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.