Description

3α,7α,12α-Trihydroxy-5β-Cholan-24-Al CAS NO 6542-40-1 is a key intermediate in the synthesis of bile acids and their derivatives, serving as a critical building block for pharmaceutical research and development. Its precise stereochemistry and functional groups make it an essential precursor for producing compounds with specific biological activity. This high-purity intermediate is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of therapeutic bile acids such as ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA).
• Biochemical Research: Used as a standard or reference compound in studies of cholesterol metabolism, liver function, and digestive processes.
• Fine Chemical Synthesis: Serves as a chiral starting material for the production of complex steroid derivatives and other specialized organic molecules.
• API Development: Employed in the research and scale-up phases for developing new active pharmaceutical ingredients (APIs) targeting hepatic and metabolic diseases.
• Diagnostic Reagents: Can be utilized in the formulation of calibration standards and reagents for clinical diagnostic kits.

Basic Information

Item	Details
Product Name	3α,7α,12α-Trihydroxy-5β-Cholan-24-Al
CAS No.	6542-40-1
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-al; 3α,7α,12α-Trihydroxy-5β-cholan-24-aldehyde; 5β-Cholan-24-al, 3α,7α,12α-trihydroxy-; Cholanaldehyde; 3α,7α,12α-Trihydroxycholanal; 24-Oxo-3α,7α,12α-trihydroxy-5β-cholane; Trihydroxycholanaldehyde
EINECS	229-471-7

Quality Control

Our 3α,7α,12α-Trihydroxy-5β-Cholan-24-Al is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.