Description

n-(2-Bromo-3-Methylbutyryl)-DL-Valine is a specialized brominated valine derivative used as a key chiral building block and intermediate in advanced organic synthesis. This compound is valued for its role in introducing specific structural motifs and facilitating stereoselective transformations. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Peptide Mimetic Synthesis: Used to incorporate modified valine residues into peptide chains to alter biological activity and stability.
• Agrochemical Research: Serves as an intermediate in the development of new pesticides and herbicides with targeted modes of action.
• Chiral Auxiliary/Reagent: Utilized in asymmetric synthesis to induce chirality in the formation of new carbon-carbon or carbon-heteroatom bonds.
• Chemical Biology Probes: Acts as a precursor for labeled compounds or probes used to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	n-(2-Bromo-3-Methylbutyryl)-DL-Valine
CAS No.	6491-38-9
Molecular Formula	C10H18BrNO3
Molecular Weight	280.16 g/mol
Synonyms	2-Bromo-3-methylbutyryl-DL-valine; DL-Valine, N-(2-bromo-3-methyl-1-oxobutyl)-; N-(2-Bromo-3-methylbutanoyl)-DL-valine; 2-Bromo-3-methylbutyric acid valine amide; (RS)-2-(2-Bromo-3-methylbutanamido)-3-methylbutanoic acid; Bromomethylbutyryl valine; Valine bromomethylbutyramide
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-3-Methylbutyryl)-DL-Valine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.