Description

Nicotinic Acid Adenine Dinucleotide (NAAD) is a crucial pyridine nucleotide coenzyme and a direct biosynthetic precursor to the essential redox cofactor NAD+. This high-purity biochemical is vital for research and development in metabolic pathways, enzyme kinetics, and cellular energy production studies. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in life science research, drug discovery, and diagnostic assay development.

Application

• Enzymology & Biochemical Research: As a substrate or precursor in studies of NAD+ biosynthesis, sirtuin activity, and ADP-ribosyl transferases.
• Pharmaceutical Development: Used in high-throughput screening assays for drug candidates targeting NAD+-dependent enzymes and metabolic disorders.
• Diagnostic Reagent Manufacturing: A key component in formulating enzymatic test kits for clinical diagnostics and research use.
• Cell Biology & Metabolism Studies: Investigating cellular redox states, mitochondrial function, and calcium signaling pathways.
• Nutraceutical & Cosmetic Research: Exploring potential applications in formulations aimed at influencing cellular NAD+ levels.
• Academic Research: Fundamental research in biochemistry, molecular biology, and plant physiology.

Basic Information

Product Name	Nicotinic Acid Adenine Dinucleotide
CAS No.	6450-77-7
Molecular Formula	C21H27N7O14P2
Molecular Weight	663.43 g/mol
Synonyms	NAAD; Deamido-NAD; Nicotinic Acid Adenine Dinucleotide Phosphate (obsolete); 3-Carboxyamide-NAD; β-NAAD; Adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt; Deamino-NAD; Nicotinate adenine dinucleotide
EINECS	229-236-6

Quality Control

Our Nicotinic Acid Adenine Dinucleotide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and spectrophotometric assays to ensure identity and potency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage under inert atmosphere, please contact our technical team.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	3.0 - 5.0
Extinction Coefficient (ε259)	17,800 - 18,200 L·mol-1·cm-1
Biological Activity	Tested in enzymatic assay system

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.