Description

Pyrrolidine, 1-(Trifluoroacetyl)- (7Ci,8Ci,9Ci) is a versatile trifluoroacetylated heterocyclic amine building block. This compound is essential for introducing the trifluoroacetyl group, a key moiety known for enhancing metabolic stability and lipophilicity in advanced molecular structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroacetyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and other complex organic transformations.
• Material Science Research: Employed in the development of novel polymers, coatings, and electronic materials that require fluorine-containing components for specific performance characteristics.
• Chemical Biology & Proteomics: Utilized as a reagent for modifying peptides and proteins, aiding in structural studies and the development of biochemical probes.

Basic Information

Product Name	Pyrrolidine, 1-(Trifluoroacetyl)- (7Ci,8Ci,9Ci)
CAS No.	6442-87-1
Molecular Formula	C6H8F3NO
Molecular Weight	167.13 g/mol
Synonyms	1-(Trifluoroacetyl)pyrrolidine; N-(Trifluoroacetyl)pyrrolidine; Pyrrolidine, 1-(trifluoroacetyl)-; Trifluoroacetic acid pyrrolidide; 2,2,2-Trifluoro-1-(pyrrolidin-1-yl)ethanone; N-Pyrrolidyl trifluoroacetamide; 1-Trifluoroacetylpyrrolidine; N-Trifluoroacetylpyrrolidine
EINECS	229-229-8

Quality Control

Our Pyrrolidine, 1-(Trifluoroacetyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.