Description

Tris(Pyrrolidinophosphine) Oxide is a specialized organophosphorus compound that serves as a versatile ligand and intermediate in advanced chemical synthesis. Its value lies in its ability to coordinate with various metal centers, facilitating catalytic processes and the creation of complex molecular architectures. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, high-performance building blocks for their development and production workflows.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in metal-catalyzed cross-coupling reactions.
• Catalyst Ligand: Acts as a ligand for transition metal catalysts in organic synthesis, including hydrogenation and hydroformylation reactions.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides as a key synthetic building block.
• Polymer Chemistry: Utilized in the production of specialized polymers and as a modifier for polymer properties.
• Coordination Chemistry: Serves as a model compound for studying phosphine oxide coordination behavior with various metals.
• Material Science: Investigated for use in the creation of advanced materials, such as flame retardants or metal-organic frameworks (MOFs).

Basic Information

Product Name	Tris(Pyrrolidinophosphine) Oxide
CAS No.	6415-07-2
Molecular Formula	C12H24N3OP3
Molecular Weight	319.26 g/mol
Synonyms	Tris(pyrrolidinophosphine) oxide; Tris(1-pyrrolidinyl)phosphine oxide; Phosphoric triamide, N,N,N',N',N'',N''-hexamethyl-, P-oxide; Hexamethylphosphoramide trioxide (HMPA trioxide); P,P,P-Tris(pyrrolidino)phosphine oxide; 1,1',1''-Phosphinylidynetrispyrrolidine oxide; Tris(N-pyrrolidinyl)phosphine oxide
EINECS	Contact for details

Quality Control

Our Tris(Pyrrolidinophosphine) Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.