Description

1,1',1''-Phosphinylidynetrispyrrolidine is a versatile organophosphorus compound, specifically a tertiary phosphine ligand, valued for its strong electron-donating properties and steric bulk. This makes it a crucial component in advanced catalytic systems, particularly in cross-coupling reactions essential for pharmaceutical and fine chemical synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new synthetic routes and optimizing existing processes. The compound, CAS 6415-02-7, is a key building block for creating high-value, complex molecules.

Application

• Homogeneous Catalysis: As a highly effective ligand for palladium, nickel, and other transition metal catalysts in cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
• Pharmaceutical Intermediates: Enabling the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides.
• Material Science: Acting as a precursor or ligand in the synthesis of novel polymers and electronic materials.
• Organic Synthesis: Facilitating challenging carbon-heteroatom bond formations and other key transformations in laboratory and pilot-scale research.
• Ligand for Asymmetric Catalysis: Potential use in chiral variants for enantioselective synthesis.

Basic Information

Product Name	1,1',1''-Phosphinylidynetrispyrrolidine
CAS No.	6415-02-7
Molecular Formula	C12H24N3P
Molecular Weight	241.31 g/mol
Synonyms	Tris(pyrrolidino)phosphine; Phosphorous tri(pyrrolidide); Tris(pyrrolidin-1-yl)phosphine; 1,1',1''-Phosphorous triyltripyrrolidine; P(Pyrrolidino)3; P(NC4H8)3; Tris(1-pyrrolidinyl)phosphine; Tris(N-pyrrolidinyl)phosphine
EINECS	229-149-7

Quality Control

Our 1,1',1''-Phosphinylidynetrispyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for catalytic and synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.